Despite the fact that Configuration Editor cannot be accessed while Virtual Machine is running, you can connect and disconnect additional devices and even choose media type they access. The following virtual devices can be connected/disconnected to the running Virtual Machine:
To connect/disconnect any device, it should be enabled in the Virtual Machine configuration. If you have disabled some device, you should stop the Virtual Machine first, then enable the device in Configuration Editor. After that you may restart the Virtual Machine, the device can be connected/disconnected in runtime environment.
Additionally, you can change the type of media the CD/DVD-ROM and floppy drives access.
USB Devices
If you start the Virtual Machine with the USB controller enabled, you may connect to the Virtual Machine different real USB peripherals. The USB controller itself can not be connected or disconnected.